Moderna expects to start late-stage COVID-19 vaccine trial on July 27

NEW YORK (Reuters) – Moderna Inc said on Tuesday it plans to start a late stage clinical trial for its COVID-19 vaccine candidate on or around July 27, according to its listing for the phase 3 study at clinicaltrials.gov.

Moderna said it will conduct the trial at 87 study locations, all in the United States.

The experimental vaccine will be tested in 30 states and Washington, D.C. Around half of the study locations are in hard-hit states like Texas, California, Florida, Georgia, Arizona and North and South Carolina.

The United States has reported record numbers of new coronavirus cases in recent days, with much of the surge coming from those states.

The federal government is supporting Moderna’s vaccine project with nearly half a billion dollars and has chosen it as one of the first to enter large-scale human trials.

Tensions between the company and government scientists contributed to a delay of the trial launch, Reuters reported earlier this month.

Shares of Moderna rose about 2.5% on Nasdaq at midday.

(Reporting by Michael Erman, Editing by Franklin Paul and Richard Chang)

3M, MIT partner to make rapid COVID-19 antigen test

By Carl O’Donnell

(Reuters) – U.S. industrial conglomerate 3M Co has partnered with the Massachusetts Institute of Technology to develop a rapid antigen test for COVID-19, the company said on Tuesday.

The test would produce results within minutes and could be administered on a low-cost, paper-based device, similar to a home pregnancy test, that could be delivered at the point of care.

“We are seeking to improve the speed, accessibility and affordability of testing for the virus, a major step in helping to prevent its spread,” said John Banovetz, the chief technology officer at 3M.

The research effort is being aided by a grant from the National Institutes of Health, which is running a project called Rapid Acceleration of Diagnostics (RADx) that funds the development of new testing technologies in academia and business.

The program aims to have the new tests available for use by late summer or early fall.

Antigen tests scan for proteins that can be found on or inside a virus. They can detect the virus very quickly and can potentially be produced at a lower cost than other tests.

3M says it could scale manufacturing to millions of tests per day once it is developed.

(Reporting by Carl O’Donnell; Editing by Leslie Adler)

Ukraine: it’s too early to blame human error for downing of passenger plane in Iran

KYIV (Reuters) – Ukraine’s foreign minister said on Tuesday it was soon to blame human error for the shooting down of a Ukrainian passenger airliner near Tehran in January, challenging the findings of Iran’s Civil Aviation Organisation (CAO).

The CAO said in an interim report that the plane was accidentally downed, killing 176 people on board, because of a misalignment of a radar system and lack of communication between the air defense operator and his commanders.

But Ukrainian Foreign Minister Dmytro Kuleba told an online briefing that many questions remained unanswered.

“I want to clearly emphasize: it is early to say that the plane was shot down as a result of human error, as the Iranian side claims,” he said. “We have many questions, and we need a large number of authoritative, unbiased, objective answers about what happened.”

Iran’s Revolutionary Guards shot down the Ukraine International Airlines flight with a ground-to-air missile on Jan. 8 shortly after the plane took off from Tehran. Iran later called it a “disastrous mistake” by forces who were on high alert during a confrontation with the United States.

Tehran last month said it would send the black box flight recorders from the downed airliner to France for analysis and that experts from the United States, Canada, France, Britain and Ukraine would take part in the decoding.

Kuleba said an Iranian delegation was due to arrive in Kiev later this month to discuss compensation. Ukrainian President Volodymyr Zelenskiy said in February Kiev was not satisfied with the size of compensation Iran had offered.

(Reporting by Pavel Polityuk, Editing by Timothy Heritage)

U.S. rejects China’s claims in South China Sea, adding to tensions

By Humeyra Pamuk, Arshad Mohammed and Yew Lun Tian

WASHINGTON/BEIJING (Reuters) – The United States on Monday rejected China’s claims to offshore resources in most of the South China Sea, drawing criticism from China which said the U.S. position raised tension in the region, highlighting an increasingly testy relationship.

China has offered no coherent legal basis for its ambitions in the South China Sea and for years has been using intimidation against other Southeast Asian coastal states, U.S. Secretary of State Mike Pompeo said in a statement.

“We are making clear: Beijing’s claims to offshore resources across most of the South China Sea are completely unlawful, as is its campaign of bullying to control them,” said Pompeo, a prominent China hawk within the Trump administration.

The United States has long opposed China’s expansive territorial claims on the South China Sea, sending warships regularly through the strategic waterway to demonstrate freedom of navigation there. Monday’s comments reflect a harsher tone.

“The world will not allow Beijing to treat the South China Sea as its maritime empire,” Pompeo said.

The U.S. statement supports a ruling four years ago under the UN Convention on the Law of the Sea (UNCLOS) that invalidated most of China’s claims for maritime rights in the South China Sea.

Chinese foreign ministry spokesman Zhao Lijian condemned the U.S. rejection of China’s claim.

“It intentionally stirs up controversy over maritime sovereignty claims, destroys regional peace and stability and is an irresponsible act,” he said at a regular briefing.

“The U.S. has repeatedly sent large fleets of sophisticated military planes and ships to the South China Sea … The U.S. is the troublemaker and destroyer of regional peace and stability.”

China claims 90% of the potentially energy-rich South China Sea, but Brunei, Malaysia, the Philippines, Taiwan and Vietnam also lay claim to parts of it.

About $3 trillion worth of trade passes through the waterway each year. China has built bases atop atolls in the region but says its intentions are peaceful.

MORE CONFIDENT?

Analysts said it would be important to see if other countries adopted the U.S. stance and what, if anything, Washington might do to reinforce its position and prevent Beijing from creating “facts on the water” to buttress its claims.

“The Southeast Asian claimants, especially Vietnam, will feel more confident in asserting their jurisdictional rights under UNCLOS,” said Ian Storey, senior fellow at the ISEAS-Yusof Ishak Institute in Singapore.

The Philippines strongly supported a rules-based order in the South China Sea and urged China to comply with the four-year-old arbitration ruling, its defense minister, Delfin Lorenzana, said.

Taiwan welcomed the U.S. statement.

“Our country opposes any attempt by a claimant state to use intimidation, coercion, or force to resolve disputes,” Taiwan foreign ministry spokeswoman Joanne Ou told reporters.

The relationship between the United States and China has grown increasingly tense recently over various issues including China’s handling of the novel coronavirus and its tightened grip on Hong Kong.

China routinely outlines the scope of its claims in the South China Sea with reference to a so-called nine-dash line on its maps that encompasses about nine-tenths of the 3.5-million-square-kilometer waters.

“This is basically the first time we have called it illegitimate,” Chris Johnson, an analyst with the Center for Strategic and International Studies, said of Pompeo’s statement.

“It’s fine to put out a statement, but what you going to do about it?”

(Reporting by Humeyra Pamuk, Arshad Mohammed, Matt Spetalnick, Daphne Psaledakis. Additional reporting by Yew Lun Tian in Beijing, Ben Blanchard in Taipei, and Karen Lema in Manila; Editing by Leslie Adler and Lincoln Feast, Robert Birsel)

U.S. executes first prisoner in 17 years after Supreme Court gives OK at 2 a.m.

(Reuters) – The U.S. government on Tuesday carried out its first execution in 17 years, putting to death convicted murderer Daniel Lee after the Supreme Court cleared the way with a ruling issued at two o’clock in the morning.

Lee was pronounced dead at 8:07 a.m. EDT (1207 GMT), U.S. Bureau of Prisons spokeswoman Kristie Breshears said by phone.

The execution had been held up by a U.S. District Court in Washington, which on Monday ordered the U.S. Justice Department to delay four executions scheduled for July and August. The order was later affirmed by an appellate court.

But at 2:10 a.m. (0610 GMT), about 10 hours after Lee’s execution was due to take place in Terre Haute, Indiana, the Supreme Court in a 5-4 vote cleared the way for federal executions to resume.

“The plaintiffs in this case have not made the showing required to justify last-minute intervention by a Federal Court. Last-minute stays like that issued this morning should be the extreme exception, not the norm,” the Supreme Court said.

Lee was convicted of killing three members of an Arkansas family in 1996, but some relatives of his victims opposed him receiving the death sentence.

Strapped to a gurney, Lee was asked if had any last words, according to a media witness present in the viewing chamber.

“I didn’t do it. I’ve made a lot of mistakes in my life but I’m not a murderer,” Lee said, according to a reporter who witnessed the execution and issued a report for all media. “You’re killing an innocent man.”

As the drug was being administered, Lee raised his head to look around, and his breathing appeared to become labored, according to the pool report. Soon after, Lee’s chest was no longer moving, his lips turned blue and his fingers became ashy.

Two unnamed Bureau of Prisons officials and Lee’s spiritual adviser could be seen inside the execution chamber.

While several states conduct executions, the federal government had not done so since 2003.

Attorney General William Barr announced last July that the Justice Department would resume carrying out executions of some of the 62 inmates on federal death row.

(Reporting by Peter Szekely, Daniel Trotta and Jonathan Allen; Editing by Andrew Heavens and Jonathan Oatis)

What you need to know about the coronavirus right now

(Reuters) – Here’s what you need to know about the coronavirus right now:

Restrictions reimposed across Asia-Pacific region

From Melbourne to Manila, Hong Kong and India’s tech capital Bengaluru, lockdowns and strict social distancing restrictions are being reimposed across the Asia-Pacific after a surge in new coronavirus cases fanned fears of a second wave of infections.

Many parts of Asia, the region first hit by the coronavirus that emerged in central China late last year, are finding cause to pause the reopening of their economies, some after winning praise for their initial responses to the outbreak.

The number of coronavirus infections around the world hit 13 million on Monday, according to a Reuters tally, climbing by a million in just five days. Reuters’ global tally, which is based on government reports, shows COVID-19 accelerating fastest in Latin America, the number of deaths there exceeding the figure for North America for the first time on Monday.

Shutdown in California

California’s governor on Monday clamped new restrictions on businesses as coronavirus cases and hospitalizations soared, and the state’s two largest school districts, in Los Angeles and San Diego, said children would be made to stay home in August.

Governor Gavin Newsom, a Democrat, ordered bars closed and restaurants, movie theaters, zoos and museums across the nation’s most populous state to cease indoor operations. Gyms, churches and hair salons must close in the 30 hardest-hit counties.

“It’s incumbent upon all of us to recognize soberly that COVID-19 is not going away any time soon, until there is a vaccine and/or an effective therapy,” Newsom said at a news briefing.

The decision to cancel in-person classes puts the districts at odds with U.S. President Donald Trump, who has said he might withhold federal funding or remove tax-exempt status from school systems that refuse to reopen.

‘Worst-case’ winter toll

Britain faces a potentially more deadly second wave of COVID-19 in the coming winter that could kill up to 120,000 people over nine months in a worst-case scenario, health experts said on Tuesday.

With COVID-19 more likely to spread in winter as people spend more time together in enclosed spaces, a second wave of the pandemic “could be more serious than the one we’ve just been through,” said Stephen Holgate, a professor and co-lead author of a report by Britain’s Academy of Medical Sciences.

“This is not a prediction, but it is a possibility,” Holgate told an online briefing. “Deaths could be higher with a new wave of COVID-19 this winter, but the risk of this happening could be reduced if we take action immediately.”

The United Kingdom’s current death toll from confirmed cases of COVID-19 is around 45,000, the highest in Europe.

Good news from hard-hit Belgium

Belgium, which has reined in the coronavirus after becoming the worst-hit mid-sized country in the world, reported zero new coronavirus-related deaths in 24 hours on Tuesday for the first time since March 10.

As in many European countries that were hard-hit by the pandemic in March and April, Belgium sharply reduced infections by imposing a lockdown, which is now being lifted.

The total number of deaths reported by the national public health institute Sciensano remained at 9,787. In the country of 11.5 million people, that works out to around 850 deaths per million, the worst in the world apart from the tiny city state of San Marino. The peak daily death toll was 343 on April 12.

Bastille Day with a difference

France held a scaled-down annual Bastille Day celebration on Tuesday, with none of the usual tanks and troops parading down Paris’s Champs Elysees avenue, in a concession to the COVID-19 epidemic still stalking Europe.

Instead, President Emmanuel Macron, standing in the back of a military jeep, reviewed ranks of socially-distanced troops on the Place de la Concorde square after a flypast by military aircraft.

“I wish, with all the French, with the armies themselves, to pay a vibrant tribute to health workers and those who, in all sectors, have enabled public, social and economic life to continue,” Macron said in message released ahead of the parade.

(Compiled by Linda Noakes and Karishma Singh; editing by Emelia Sithole-Matarise)

White House names Kratsios as Pentagon acting tech chief

FILE PHOTO: The Pentagon in Washington, U.S., is seen from aboard Air Force One, March 29, 2018. REUTERS/Yuri Gripas/File Photo

By David Shepardson

WASHINGTON (Reuters) – The Pentagon confirmed on Monday that U.S. Chief Technology Officer Michael Kratsios is being tapped to serve as the acting Under Secretary of Defense for Research and Engineering overseeing the U.S. military’s massive R&D efforts.

Kratsios, who is President Donald Trump’s top technology policy advisor, will also serve as the acting Pentagon chief technology officer. Reuters reported the planned move earlier on Monday.

The Defense Department has the largest research and development budget in the federal government and Kratsios will oversee the Missile Defense Agency, the Defense Advanced Research Projects Agency (DARPA), the Defense Innovation Unit, Space Development Agency and the DoD Laboratory enterprise.

Defense Secretary Mark Esper said in a statement the Pentagon sought “someone with experience in identifying and developing new technologies and working closely with a wide range of industry partners. We think Michael is the right person for this job.”

On June 23, the Pentagon said its chief technology officer Mike Griffin, an outspoken advocate for space-based missile defense systems, and his deputy Lisa Porter would resign effective July 10 to set up their own company.

The Pentagon also confirmed Monday that Mark J. Lewis, director of Defense Research and Engineering for Modernization, will serve as Kratsios’ acting deputy at the Pentagon.

Kratsios will also oversee the agency’s Modernization Priorities, which include efforts on 5G, artificial intelligence, quantum computing, and microelectronics. Kratsios led the development of the White House’s national strategies for AI, 5G, and quantum computing.

Kratsios has also worked on autonomous vehicles, commercial drones and advanced manufacturing at the White House. He will retain his White House role along with the Pentagon assignment.

(Reporting by David Shepardson; Editing by Richard Chang)

Florida sets one-day record with over 15,000 new COVID cases, more than most countries

By Lisa Shumaker

(Reuters) – Florida reported a record increase of more than 15,000 new cases of COVID-19 in 24 hours on Sunday, as the Trump administration renewed its push for schools to reopen and anti-mask protests were planned in Michigan and Missouri.

If Florida were a country, it would rank fourth in the world for the most new cases in a day behind the United States, Brazil and India, according to a Reuters analysis.

Florida’s daily increases in cases have already surpassed the highest daily tally reported by any European country during the height of the pandemic there. It has also broken New York state’s record of 12,847 new cases on April 10 when it was the epicenter of the U.S. outbreak.

The latest rise was reported a day after Walt Disney World in Orlando reopened with a limited number of guests who were welcomed with a host of safety measures, including masks and temperature checks.

Anti-mask activists in several states, including Florida and Michigan, have organized protests against local mandates, arguing that the measures infringe upon individual freedom.

Coronavirus infections are rising in about 40 states, according to a Reuters analysis of cases for the past two weeks compared with the prior two weeks. Nationally, the United States has broken global records by registering about 60,000 new cases a day for the last four days in a row, according to a Reuters tally. Hospitalizations and positive test rates are also rising in Arizona, California, Florida and Texas.

Florida reported a record amount of testing, with nearly 143,000 results announced on Sunday compared with an average of 68,000 for the prior seven days.

TRUMP DONS MASK

Facing a battered economy as he seeks re-election in November, President Donald Trump has pressured states to reopen shuttered businesses and schools.

Education Secretary Betsy DeVos said on Sunday that her department did not have its own safe reopening plans to promote, and each school district and state must devise their own plans based on their local coronavirus infection rates.

Health officials have pleaded with the public to wear masks to limit the spread of the virus, but the issue has become politically divisive in the United States unlike many other countries that have seen far lower rates of infection and death.

Seven months into the pandemic, Trump wore a mask for the first time in public when he visited a Washington D.C.-area military medical center on Saturday. He had previously refused to wear a mask in public or ask Americans to wear face coverings, saying it was a personal choice.

Many Americans still refuse to wear a mask, which health experts say help stop transmission of the virus that has killed more than 134,000 Americans.

Anti-mask activists organized a protest on Saturday at a grilled cheese restaurant and bar in Windermere, Florida, which is in Orange County about 12 miles (19 km) from Walt Disney World.

The restaurant, 33 & Melt, has become a focal point of tension after owner Carrie Hudson said she was not requiring customers to wear masks. County officials have mandated the use of masks in public since June 20.

During Saturday’s protest, no customers wore face coverings inside the restaurant. Agents from the state’s Division of Alcoholic Beverages and Tobacco arrived during the rally and served Hudson with a warning, according to a video.

“This is a virus that is very well contained,” said one of the demonstrators, anti-mask activist Tara Hill. “Everyone is responsible for their own health care decisions … We want our choices respected as well.”

In addition to a record 15,000 new cases on Sunday, more than four dozen hospitals in Florida reported that their intensive care units are full due to a surge in COVID-19 patients.

Hundreds were expected to attend a demonstration at the Michigan state capitol on Sunday afternoon, according to a Facebook event, to protest against Governor Gretchen Whitmer’s order that everyone must wear a mask in public, except when outdoors and able to maintain social distance.

Protesters were also planning to gather outside city hall in Springfield, Missouri on Monday, where the city council was due to vote on a mask mandate in response to rising cases and a more than fourfold increase in Greene County’s COVID-19 hospitalizations in the last month.

(Reporting by Gabriella Borters in New York and Octavio Jones in Windermere, Florida; Writing by Lisa Shumaker; Editing by Daniel Wallis)

U.S. judge delays first federal executions in 17 years

By Jonathan Allen

(Reuters) – A U.S. federal judge issued an injunction on Monday stopping what would have been the first federal execution in 17 years, scheduled for later in the day, to allow the continuation of legal challenges against the government’s lethal-injection protocol.

Judge Tanya Chutkan of the U.S. district court in Washington ordered the U.S. Department of Justice to delay four executions the department had scheduled for July and August until further order of the court.

Efforts to resume capital punishment at the federal level were underway within a few months of President Donald Trump’s inauguration in 2017, ending a de facto moratorium that began under his predecessor, Barack Obama, while long-running legal challenges to lethal injections played out in federal courts.

Judge Chutkan has been overseeing cases brought by inmates on death row who argue that the Justice Department’s new one-drug protocol breaks various administrative and drug-control laws and is unconstitutional.

The Justice Department had planned to execute Daniel Lewis Lee on Monday in Terre Haute, Indiana, using lethal injection of pentobarbital, a powerful barbiturate, for his role in the murders of three members of an Arkansas family, including an 8-year-old child, in 1996.

Some relatives of Lee’s victims opposed him receiving the death sentence while his accomplice in the murders, Chevie Kehoe, was sentenced to life in prison.

The department had scheduled two more executions for later in the week and a fourth in August, of Wesley Purkey, Dustin Honken and Keith Nelson, all convicted of murdering children.

The coronavirus pandemic has prevented some of the lawyers of inmates on death row from visiting their clients. At least one employee involved in the executions tested positive for COVID-19, the Justice Department said over the weekend.

On Sunday, an appeals court rejected an argument by some relatives of Lee’s victims, who sued for a delay saying they feared that attending his execution could expose them to the coronavirus.

FEDERAL EXECUTIONS RARE

While Texas, Missouri and other states execute multiple condemned inmates each year, federal executions are rare: only three have occurred since 1963, all from 2001 to 2003, including the 2001 execution of Oklahoma City bomber Timothy McVeigh.

There are currently 62 people on federal death row in Terre Haute.

Opposition to the death penalty has grown in the United States, although 54 percent of Americans said they supported it for people convicted of murder, according to a 2018 survey by the Pew Research Center.

In announcing the planned resumption of executions, Attorney General William Barr said last year: “We owe it to the victims and their families to carry forward the sentence imposed by our justice system.”

A European Union ban on selling drugs for use in executions or torture has led to pharmaceutical companies refusing to sell such drugs to U.S. prison systems.

The Justice Department spent much of 2018 and 2019 building a secret supply chain of private companies to make and test its drug of choice, pentobarbital, which replaces the three-drug protocol used in previous executions. Some of the companies involved said they were not aware they were testing execution drugs, a Reuters investigation found last week.

As with Texas and other states, the Justice Department has commissioned a private pharmacy to make the drug.

(Reporting by Jonathan Allen in New York; Editing by Peter Cooney and Dan Grebler)

 

Global coronavirus cases rise above 13 million

By Gayle Issa

(Reuters) – Global coronavirus infections passed 13 million on Monday, according to a Reuters tally, marking another milestone in the spread of the disease which has killed more than half a million people in seven months.

The first case was reported in China in early January and it took three months to reach one million cases. It has taken just five days to climb to 13 million cases from 12 million recorded on July 8.

The number of cases is around triple that of severe influenza illnesses recorded annually, according to the World Health Organization.

There have been more than 568,500 deaths linked to the coronavirus so far, within the same range as the number of yearly influenza deaths reported worldwide. The first death was reported on Jan. 10 in Wuhan, China, before infections and fatalities surged in Europe and then later in the United States.

Many hard-hit countries are easing lockdowns put in place to slow the spread of COVID-19. Other places, such as the Australian city of Melbourne, are implementing a second round of shutdowns.

The Reuters tally, which is based on government reports, shows the disease is accelerating the fastest in Latin America. The Americas account for more than half the world’s infections and half the deaths.

The United States reported a daily global record of 69,070 new infections on July 10. In, 1.86 million people have tested positive, including President Jair Bolsonaro, and more than 72,000 people have died.

India, the country with the third-highest number of infections, has been contending with an average of 23,000 new infections each day since the beginning of July.

In countries with limited testing capacity, case numbers reflect only a proportion of total infections. Experts say official data likely under-represents both infections and deaths.

(Reporting by Gayle Issa; Editing by Frances Kerry, Nick Macfie and Toby Chopra)