France kicks off Europe’s vaccine donations to poorer states

PARIS (Reuters) – France will donate an initial 100,000 doses of AstraZeneca’s COVID vaccine to developing countries this month, the first European Union member to send its own supplies to the COVAX initiative for poorer countries, an official said on Wednesday.

French President Emmanuel Macron has urged EU countries to send 5% of their own vaccine supplies to developing countries to hamper the development of new variants and stop Russia and China from gaining a diplomatic advantage by sharing their shots.

“France will inaugurate the European vaccine sharing mechanism with COVAX,” an adviser to Macron said on Wednesday. “We very much hope that other countries will commit to physically sharing vaccines with COVAX.”

The COVAX facility, backed by the World Health Organization (WHO) and the Global Alliance for Vaccines and Immunization (GAVI), aims to secure 2 billion vaccine doses for lower-income countries by the end of 2021.

In March, it said the target was to deliver 237 million doses of AstraZeneca’s shot to 142 countries by the end of May, and it also shipped its first Pfizer shots.

French officials have expressed concern that developed countries around the globe, which are rushing to vaccinate their own population, have only committed cash to COVAX and refrained from sending doses from their own reserves.

France has committed to sending 500,000 doses by mid-June, the French adviser said. The first batch of AstraZeneca doses, taken from France’s own expected deliveries, will be sent to COVAX “imminently,” the adviser said.

(Reporting by Michel Rose; editing by Philippa Fletcher)

Global officials urge rich countries to donate excess COVID-19 vaccine doses, money

By Stephanie Nebehay and Michelle Nichols

GENEVA/NEW YORK (Reuters) -Top U.N., financial and vaccine officials on Thursday urged rich countries to donate excess COVID-19 vaccine doses to an international effort to supply low and middle income countries in a bid to get the global economy back on track.

At a virtual event by the Gavi Vaccine Alliance to boost support for the COVAX equitable vaccine sharing initiative, the officials also appealed for another $2 billion by June for the program, which is aiming to buy up to 1.8 billion doses in 2021. So far, COVAX has shipped more than 38 million vaccine doses to 111 countries.

“Global supply is incredibly tight right now. But we also know that many high income countries have ordered more vaccines than they need,” said Gavi Chief Executive Seth Berkley.

He urged them to share excess doses “as soon as possible to cover the high risk populations during this supply constrained period.”

New Zealand Prime Minister Jacinda Ardern announced a donation of enough vaccine doses for more than 800,000 people to COVAX, which is run by the Coalition for Epidemic Preparedness Innovations (CEPI), the Vaccine Alliance Gavi, the World Health Organization (WHO) and U.N. Children’s Fund (UNICEF).

Denmark, the Netherlands, Norway and Sweden all pledged new funds to COVAX on Thursday.

“Many countries now have dollars available to spend on doses, but rapid deliveries aren’t available. I would like to underline here the importance for countries that have the prospect of excess vaccine supplies to release them as soon as possible,” said World Bank President David Malpass.

World Health Organization (WHO) chief Tedros Adhanom Ghebreyesus said some countries who had signed up to COVAX had not received any doses, none had received enough and some were not receiving their second-round vaccine allocations on time.

“There remains a shocking and expanding disparity in the global distribution of vaccines,” he warned at the Gavi event.

UNICEF Executive Director Henrietta Fore called on wealthier countries to invest generously in COVAX and donate surplus doses because it was the only way to end the pandemic and get “the global economy back on track.”

Norwegian Prime Minister Erna Solberg said another $22 billion was needed for the Access to COVID-19 Tools (ACT) Accelerator, which includes COVAX and also supports treatments and testing.

“These numbers may seem high, but they are small compared to the global economic loss if this crisis continues. The new virus strains make it clear that we need to move faster,” she said.

(Reporting by Stephanie Nebehay in Geneva and Michelle Nichols in New York; Editing by Bill Berkrot)

WHO chief laments ‘shocking imbalance’ in COVID-19 shot distribution

GENEVA (Reuters) -There is a “shocking imbalance” in the distribution of COVID-19 vaccines worldwide and most countries do not have anywhere near enough shots to cover health workers and others at high-risk, WHO Director-General Tedros Adhanom Ghebreyesus said on Friday.

More than 700 million jabs have been administered worldwide against the disease, but 87% have gone to high income or upper middle-income countries, with low income countries receiving just 0.2%, he said.

“On average in high-income countries, almost one in four people has received a COVID-19 vaccine. In low-income countries, it’s one in more than 500,” Tedros told a briefing.

The COVAX facility has delivered nearly 38.4 million doses of COVID-19 vaccines to 102 countries across six continents, six weeks after it began to roll out supplies, the GAVI vaccine alliance and WHO said on Thursday. It aims to deliver more than 2 billion doses this year but has faced delays.

“We hope to be able to catch up during April and May. The problem is not getting vaccines out of COVAX, the problem is getting them in,” Tedros said, decrying the scarcity of supply.

The AstraZeneca shot – the mainstay of the COVAX program so far – has been hit by safety concerns after reports of blood clots in some recipients.

Australia said on Friday it had ordered more alternatives for the AstraZeneca vaccine, setting back its vaccination rollout, and Hong Kong delayed deliveries of the shot amid concern about a possible very small risk of rare blood clots.

GAVI CEO Seth Berkley, asked whether COVAX was negotiating for more doses of the vaccine being shunned by some countries, said that the Anglo-Swedish company’s supply chain had “picked up”.

He hoped that the supply of AstraZeneca vaccine made by the Serum Institute of India – whose doses are now being kept domestically for use against an accelerating epidemic – would improve over time.

“As countries decide they are going to prioritize one vaccine or another that may free up doses, and in doing we will try to make sure those doses are made available without delay, if countries are willing to make that happen,” Berkely said.

(Reporting by Stephanie Nebehay and John Revill Writing by Andrew HeavensEditing by Andrew Cawthorne and Peter Graff)

COVAX vaccines reach more than 100 countries, despite supply snags

By Stephanie Nebehay

GENEVA (Reuters) -The COVAX vaccine facility has delivered nearly 38.4 million doses of COVID-19 vaccines to 102 countries and economies across six continents, six weeks after it began to roll out supplies, according to a statement on Thursday.

The program offers a lifeline to low-income countries in particular, allowing them in the first instance to inoculate health workers and others at high risk, even if their governments have not managed to secure vaccines from the manufacturers.

But there have been some delays, the GAVI vaccine alliance and World Health Organization said in a statement.

Reduced availability of delayed some deliveries in March and April, and much of the output of the Serum Institute of India, which makes the AstraZeneca vaccine, is being kept in India, where daily infections surpassed 100,000 for the first time on Monday.

The Caribbean island of St. Lucia became the 100th country to receive vaccines through COVAX. Iran, also battling a record rate of infection, is another recent recipient.

The 102 countries reached so far include 61 benefiting from a mechanism essentially financed by donors.

WHO Director-General Tedros Adhanom Ghebreyesus on Monday called it a “travesty” that some countries still did not have enough vaccines to begin inoculating health workers and the most vulnerable.

GAVI said last month that it planned to deliver 237 million doses of the AstraZeneca vaccine – which has been produced at cost for a few dollars a dose, and does not require the advanced refrigeration of some other coronavirus vaccines – to 142 countries by the end of May.

“COVAX may be on track to deliver to all participating economies in the first half of the year, yet we still face a daunting challenge as we seek to end the acute stage of the pandemic,” GAVI chief executive Seth Berkley said in the statement.

Nonetheless, COVAX still expects to deliver at least 2 billion doses this year 2021, and to diversify the offering beyond the AstraZeneca/Oxford and Pfizer/BioNTech shots it is currently supplying.

(Reporting by Stephanie Nebehay; Editing by Kevin Liffey)

India AstraZeneca shot delay could be ‘catastrophic’ for Africa: health official

ADDIS ABABA (Reuters) – India’s temporary hold on major exports of AstraZeneca’s COVID-19 shot will undermine Africa’s vaccination plans, and could have a “catastrophic” impact if extended, the head of the continent’s disease control body said on Thursday.

India decided to delay big exports of the shots made in its territory by the Serum Institute of India (SII) to make sure it could meet local demand, two sources told Reuters last week.

The hold “will definitely impact our ability to continuously vaccinate people,” the director of the Africa Centers for Disease Control and Prevention, John Nkengasong, told a news conference in Addis Ababa.

The African Union had planned to vaccinate 30-35% of the continent’s population by the end of the year he said. “If the vaccines are delayed we are unlikely to meet our target,” he added.

That AU target primarily relies on supplies from the global COVAX vaccine-sharing facility, through which 64 poorer countries including many in Africa are supposed to get doses from the SII. COVAX aims to provide enough shots for African countries to inoculate at least 20% of their populations.

“If the delay continues, I hope it’s a delay and not a ban, that would be catastrophic for meeting our vaccinations schedule,” Nkengasong said.

African countries have reported 4.25 million coronavirus infections and 112,000 related deaths, though experts have said the actual numbers could be higher.

The AU has also been negotiating with manufacturers to help member states secure the additional doses they will need to achieve 60% coverage.

On Monday, Johnson & Johnson announced it would supply the AU with up to 400 million doses of its COVID-19 vaccine. Delivery of those doses is due to begin in the third quarter of this year and will continue through 2022.

Those doses are separate from the GAVI/WHO-backed global COVAX facility.

Nkengasong said on Thursday the AU has “pivoted” towards the J&J shot in part as a result of the delay in the delivery of AstraZeneca shots, and also because it is a single-dose shot.

The J&J doses will begin to arrive in June or July, which will ease any shortage caused by the delay in the AstraZeneca doses, Nkengasong said. The gap until the arrival of the J&J doses is a concern, he added.

(Reporting by Addis Ababa newsroom; Writing by Maggie Fick; Editing by Andrew Heavens)

Keep using AstraZeneca vaccine, WHO urges world

By Emma Farge

GENEVA (Reuters) – The World Health Organization (WHO) exhorted the world to keep administering AstraZeneca’s COVID-19 shots on Friday, adding its endorsement to that of European and British regulators after concerns over blood clotting.

“We urge countries to continue using this important COVID-19 vaccine,” WHO Director General Tedros Adhanom Ghebreyesus told a news conference in Geneva.

He was speaking after the global health body’s vaccine safety panel said available data about the AstraZeneca shot did not point to any overall increase in clotting conditions.

European and British regulators also said this week that the benefits of AstraZeneca’s shot outweighed the risks, prompting various nations to lift their suspensions.

“The AstraZeneca vaccine is especially important because it accounts for more than 90% of the vaccines being distributed through COVAX,” Tedros added, referring to a WHO-led global vaccine-sharing scheme.

“There is no question. COVID-19 is a deadly disease, and the Oxford-AstraZeneca vaccine can prevent it. It’s also important to remember that COVID-19 itself can cause blood clots and low platelets.”

The WHO’s global advisory committee on vaccine safety said in a statement that the AstraZeneca vaccine had a “positive benefit-risk profile” and “tremendous potential” to prevent infections and reduce deaths.

The WHO panel of 12 independent experts, who met virtually on Tuesday and on Thursday, reviewed safety data from Europe, the United Kingdom, India, and WHO’s global database.

“While very rare and unique thromboembolic events in combination with thrombocytopenia, such as cerebral venous sinus thrombosis (CVST), have also been reported following vaccination with the AstraZeneca COVID-19 vaccine in Europe, it is not certain that they have been caused by vaccination,” it said.

(Reporting by Michael Shields, Emma Farge and Stephanie Nebehay; Writing by Andrew Cawthorne; Editing by Hugh Lawson)

U.S. plans to send four million doses of AstraZeneca vaccine to Mexico, Canada

By Jeff Mason

WASHINGTON (Reuters) – The United States plans to send roughly 4 million doses of AstraZeneca’s COVID-19 vaccine that it is not using to Mexico and Canada in loan deals with the two countries, an administration official told Reuters on Thursday.

Mexico will receive 2.5 million doses of the vaccine and Canada will receive 1.5 million doses, the official said.

“This virus has no borders,” the official told Reuters on condition of anonymity. “We only put the virus behind us if we’re helping our global partners.”

The Biden administration has come under pressure from allies worldwide to share vaccine, particularly from AstraZeneca, which is authorized for use in other countries but not yet in the United States.

AstraZeneca has millions of doses made in a U.S. facility, and has said that it would have 30 million shots ready at the beginning of April. The company’s shares rose slightly on the news.

The deal to share the vaccine, which is still being finalized, does not affect President Joe Biden’s plans to have vaccine available for all adults in the United States by the end of May, the official said. The deal is likely to be announced publicly in the coming days.

Two officials said the vaccine would be delivered in “short order” once the deal was completed, but they declined to give a more specific timetable.

The “releasable” vaccines are ready to be used once they arrive. Under the deal, the United States will share doses with Mexico and Canada now with the understanding that they will pay the United States back with doses in return. The official said that would take place later this year.

The United States had no plans to share the vaccine with other countries at this time, he said.

“They are our neighbors, they are our partners,” the official said about Mexico and Canada. Mexican President Andres Manuel Lopez Obrador had requested the vaccine previously.

Biden has said if the United States has a surplus of vaccine, it will share it with the rest of the world.

The official noted that the United States has pledged $4 billion to the COVAX vaccine facility that aims to deliver coronavirus vaccines to poor countries.

(Reporting by Jeff Mason; Editing by Heather Timmons and Alistair Bell)

Kenya hails first vaccine ‘bazookas,’ Rwanda secures Pfizer shots

By Omar Mohammed and Clement Uwiringiyimana

NAIROBI/KIGALI (Reuters) – Kenya received over a million doses of the AstraZeneca COVID-19 vaccine on Wednesday, while Rwanda said it was the first in Africa to secure shots from Pfizer, as efforts to inoculate the world’s poorest nations accelerated.

With fewer resources and tougher logistics than other regions, African nations are racing to secure the doses needed to protect their roughly 1.3 billion people and allow the safe reopening of economies.

Africa has been relatively lightly hit by the coronavirus compared with other regions, recording 104,000 deaths, according to a Reuters tally. That is lower than national tolls in the United States, India, Brazil, Russia and Britain.

Kenya’s batch, which arrived on a Qatar Airways passenger flight, is the first of an initial allocation of 3.56 million doses by the global COVAX facility.

“We have received … machine guns, bazookas, and tanks to fight this war against COVID-19,” Health Minister Mutahi Kagwe exulted as the doses arrived at Nairobi’s main airport.

COVAX, which is led by the GAVI vaccines alliance along with the World Health Organization (WHO) and other partners, aims to deliver over 1.3 billion doses to 92 lower- and middle-income countries, covering up to 20% of their populations.

Backers of the initiative hope to level a playing field that has seen wealthier nations quickly vaccinate millions, ahead of poorer regions. Only a few African nations have started inoculating citizens with vaccines acquired outside of COVAX.

First shots under COVAX are arriving at several African nations this week, including Nigeria, Senegal and Uganda.

Senegal, which received 200,000 doses developed by China’s Sinopharm last month, got an additional 324,000 shots of the AstraZeneca vaccine on Wednesday, via COVAX.

COLD STORAGE

In Kigali, officials said Rwanda will get the first doses of the Pfizer COVID-19 shots to be dispatched to Africa under the vaccine-sharing scheme. The Pfizer vaccine presents an extra logistical challenge because it requires ultra-cold storage.

The batch of 102,960 doses were due in Kigali on Wednesday, hours after a flight landed carrying 240,000 AstraZeneca doses from the Serum Institute of India, the health ministry said. The government has installed special infrastructure to keep the vaccine at -70 degrees.

“Rwanda is one of the first countries among the low income countries to have ultra-cold chain,” said Fode Ndiaye, the United Nations’ resident coordinator.

Rwanda plans to start its vaccination drive on Friday, prioritizing frontline health workers and others at high risk. It hopes to vaccinate 30% of its roughly 12 million people before the end of this year.

Despite Africa’s comparatively low fatalities, fragile economies across the continent are reeling from lockdowns.

Kenya, which has so far recorded 106,470 infections and 1,863 deaths, has taken a major economic hit from the virus, which cut the flow of tourists, a crucial source of foreign exchange and jobs.

Nairobi plans to prioritize 400,000 health workers nationwide in a vaccination campaign starting on Friday, the health ministry said.

It will join Ivory Coast, Ghana and South Africa among the nations in sub-Saharan Africa to start vaccination drives.

(Writing by Duncan Miriri; Editing by Andrew Cawthorne)

COVAX vaccine program to deliver 237 million doses to 142 nations by end-May

GENEVA/LONDON (Reuters) – The COVAX vaccine-sharing program said on Tuesday it will deliver 237 million doses of AstraZeneca’s COVID-19 shot to 142 countries by the end of May as it steps up the global roll-out of its vaccine supplies.

The timeline for the delivery of doses, made by AstraZeneca and by India’s Serum Institute, will be split into separate two-month schedules, COVAX said in a statement, with the first in February-March and the second in April-May.

“These timelines are dependent on a variety of factors including national regulatory requirements, availability of supply, and fulfillment of other criteria such as validated national deployment and vaccination plans,” the statement said.

COVAX is the World Health Organization-backed program to provide vaccines for poor and middle-income countries. It began its roll-out last week with the first deliveries of shots to Ghana and Ivory Coast.

Hailing the campaign as an “unprecedented partnership,” WHO Director-General Tedros Adhanom Ghebreyesus said Angola, Cambodia, Democratic Republic of Congo and Nigeria could also expect deliveries of COVAX-supplied vaccines on Tuesday.

“This is an unprecedented partnership that will not only change the course of the pandemic but also change the way the world responds to future health emergencies,” Tedros told a joint media briefing with the U.N. Children’s Fund UNICEF, the GAVI vaccines alliance – which co-leads COVAX – and others.

Ghanaian President Nana Akufo-Addo told the same briefing that his West African country, which this week began its inoculation campaign with COVAX doses, aimed to vaccinate 20 million people by the end of 2021.

COVAX added in a statement that as well as the first round of allocations of the AstraZeneca vaccine, some 1.2 million doses of the Pfizer-BioNTech COVID shot were also anticipated for delivery in the first quarter of 2021.

(Reporting by Emma Farge and Stephanie Nebehay in Geneva and Kate Kelland in London; Editing by Mark Heinrich)

Global COVID-19 infections up for first time in seven weeks, WHO says

ZURICH (Reuters) – The number of new coronavirus infections globally rose last week for the first time in seven weeks, the World Health Organization said on Monday.

“We need to have a stern warning for all of us: that this virus will rebound if we let it,” Maria Van Kerkhove, the WHO technical lead for COVID-19, told a briefing. “And we cannot let it.”

WHO Director-General Tedros Adhanom Ghebreyesus said the rise in cases was “disappointing but not surprising” and urged countries not to relax measures to fight the disease.

It was too early for countries to rely solely on vaccination programs and abandon other measures, he said: “If countries rely solely on vaccines, they are making a mistake. Basic public health measures remain the foundation of the response.”

Tedros noted that Ghana and Ivory Coast became the first countries on Monday to begin vaccinating people with doses supplied by COVAX, the international program to provide vaccines for poor and middle-income countries.

But he also criticized rich countries for hoarding vaccine doses, saying that it was in everyone’s interest for vulnerable people to be protected around the world.

“It’s regrettable that some countries continue to prioritize vaccinating younger healthier adults at lower risk of diseases in their own populations, ahead of health workers and older people elsewhere,” Tedros said.

Mike Ryan, the WHO’s top emergency expert, said the global fight against the coronavirus was in a better state now than it was 10 weeks ago before the roll-outs of vaccines had begun. But it was too early to say the virus was coming under control.

“The issue is of us being in control of the virus and the virus being in control of us. And right now the virus is very much in control.”

(Reporting by John Revill, Vishwadha Chander, Manojna Maddipatla; Writing by Peter Graff; Editing by Alex Richardson, Dan Grebler and Giles Elgood)