WHO sounds warning over fast-spreading Omicron

By Stephanie Nebehay and Emma Farge

GENEVA (Reuters) -The Omicron variant of the coronavirus is spreading faster than the Delta variant and is causing infections in people already vaccinated or who have recovered from the COVID-19 disease, the head of the World Health Organization (WHO) said on Monday.

WHO chief scientist Soumya Swaminathan added it would be “unwise” to conclude from early evidence that Omicron was a milder variant that previous ones.

“… with the numbers going up, all health systems are going to be under strain,” Soumya Swaminathan told Geneva-based journalists.

The variant is successfully evading some immune responses, she said, meaning that the booster programs being rolled out in many countries ought to be targeted towards people with weaker immune systems.

“There is now consistent evidence that Omicron is spreading significantly faster than the Delta variant,” WHO director-general Tedros Adhanom Ghebreyesus told the briefing.

“And it is more likely people vaccinated or recovered from COVID-19 could be infected or re-infected,” Tedros said.

Their comments echoed the finding of study by Imperial College London, which said last week the risk of reinfection was more than five times higher and it has shown no sign of being milder than Delta.

WHO officials said however that other forms of immunity vaccinations may prevent infection and disease.

While the antibody defenses from some actions have been undermined, there has been hope that T-cells, the second pillar of an immune response, can prevent severe disease by attacking infected human cells.

WHO expert Abdi Mahamud added: “Although we are seeing a reduction in the neutralization antibodies, almost all preliminary analysis shows T-cell mediated immunity remains intact, that is what we really require.”

However, highlighting how little is known about how to handle the new variant that was only detected last month, Swaminathan also said: “Of course there is a challenge, many of the monoclonals will not work with Omicron.”

She gave no details as she referred to the treatments that mimic natural antibodies in fighting off infections. Some drug makers have suggested the same.

ENDING THE PANDEMIC

In the short term, Tedros said that holiday festivities would in many places lead to “increased cases, overwhelmed health systems and more deaths” and urged people to postpone gatherings.

“An event cancelled is better than a life cancelled,” he said.

But the WHO team also offered some hope to a weary world facing the new wave that 2022 would be the year that the pandemic, which already killed more than 5.6 million people worldwide, would end.

It pointed towards the development of second and third generation vaccines, and the further development of antimicrobial treatments and other innovations.

“(We) hope to consign this disease to a relatively mild disease that is easily prevented, that is easily treated,” Mike Ryan, the WHO’s top emergency expert, told the briefing.

“If we can keep virus transmission to minimum, then we can bring the pandemic to an end.”

However Tedros also said China, where the SARS-CoV-2 coronavirus was first detected at the end of 2019, must be forthcoming with data and information related to its origin to help the response going forward.

“We need to continue until we know the origins, we need to push harder because we should learn from what happened this time in order to (do) better in the future,” Tedros said.

(Reporting by Stephanie Nebehay and Emma Farge; Editing by Alison Williams)

What you need to know about the coronavirus right now

(Reuters) – Here’s what you need to know about the coronavirus right now:

Lawsuit consolidation set to give Biden administration a chance to revive COVID vaccine mandate

Lawsuits filed around the United States challenging the Biden administration’s workplace COVID-19 vaccine rule are expected to be consolidated in a single federal appeals court on Tuesday, giving the government a chance to revive a rule that was blocked last week.

More than a dozen lawsuits have been filed challenging the rule, which requires employers with at least 100 workers to mandate COVID-19 vaccination or weekly testing combined with wearing a face covering at work.

Pfizer to allow generic versions of its COVID-19 pill in 95 countries

Pfizer Inc said on Tuesday it will allow generic manufacturers to supply its experimental antiviral COVID-19 pill to 95 low- and middle-income countries through a licensing agreement with international public health group Medicines Patent Pool (MPP).

The voluntary licensing agreement between Pfizer and the MPPwill allow the United Nations-backed group to grant sub-licenses to qualified generic drug manufacturers to make their own versions of PF-07321332.

Pfizer will sell the pills it manufactures under the brand name Paxlovid.

Delta dominates, scientists watch for worrisome offspring

The Delta variant of the SARS-CoV-2 virus now accounts for nearly all coronavirus infections globally and virus experts are closely watching its evolution, looking for signs of mutation.

According to the WHO, Delta makes up 99.5% of all genomic sequences reported to public databases and has “outcompeted” other variants in most countries.

A key exception is South America, where Delta has spread more gradually, and other variants previously seen as possible global threats – notably Gamma, Lambda and Mu – still contribute to a significant proportion of reported cases.

Japan plans to ease quarantine rules – report

Japan intends to ease quarantine rules by the end of November for people inoculated with Johnson & Johnson’s COVID-19 vaccine, the Nikkei daily reported on Tuesday.

Last week the country took a first step in its planned phased re-opening of borders, which centers on business travelers.

Germany could make COVID test or vaccine mandatory for public transport

Want to take the bus or train in Germany? You may soon have to provide a negative COVID-19 test, or proof of vaccination or recent recovery, as the country becomes the latest in Europe to consider drastic steps to tackle a new surge in cases in the region.

The center-left Social Democrats, Greens and pro-business FDP said on Monday they would add harsher measures to their draft law under parliamentary consideration to deal with the outbreak.

India’s Dr. Reddy’s open to making Pfizer pill

Dr. Reddy’s Laboratories, one of a handful of Indian drug companies licensed to make a new COVID-19 pill developed by Merck, said on Monday it was open to making a similar pill from Pfizer thought to be even more effective.

The new drugs, which unlike vaccines can be used to treat patients once they contract coronavirus infections, are expected to have a huge market.

Merck has licensed manufacturers in developing countries to ensure swift global supply, and companies are hopeful that Pfizer will do the same.

(Compiled by Karishma Singh and Ed Osmond; Editing by Jan Harvey)

U.S. weekly jobless claims near 20-month low; labor costs surge

By Lucia Mutikani

WASHINGTON (Reuters) – The number of Americans filing new claims for unemployment benefits fell to the lowest level in nearly 20 months last week, suggesting the economy was regaining momentum amid a significant improvement in public health, though supply constraints remain.

The tightening labor market is driving up wages as companies scramble for workers, contributing to keeping inflation high. Labor costs surged in the third quarter, other data showed on Thursday, with productivity sinking at its steepest pace in 40 years. The Federal Reserve announced on Wednesday that it would this month start scaling back the amount of money it is pumping into the economy through monthly bond purchases.

“Firms are reluctant to lay off workers with strong demand and labor in short supply,” said Gus Faucher, chief economist at PNC Financial in Pittsburgh, Pennsylvania. “The big open question is what is happening to the millions of people who lost their benefits in September, or saw their benefits drop.”

Initial claims for state unemployment benefits fell 14,000 to a seasonally adjusted 269,000 for the week ended Oct. 30, the Labor Department said. That was the lowest level since the middle of March in 2020, when mandatory business closures were being enforced to slow the first wave of COVID-19 infections. Claims have now declined for five straight weeks.

Unadjusted claims, which economists say offer a better read of the labor market, fell 7,114 to 240,216 last week. There were significant declines in filings in Missouri and Florida, which offset increases in California and Kentucky.

Claims in Kentucky were likely boosted by temporary layoffs in the automobile sector as motor vehicle manufacturers cut production because of scarce semiconductors.

The summer wave of infections driven by the Delta variant has subsided, encouraging more Americans to travel, dine out and frequent sporting venues among activities that were curtailed by the resurgence in cases. The Delta variant and shortages of goods contributed to restricting economic growth to its slowest pace in more than a year last quarter.

Claims, which have declined from a record high of 6.149 million in early April 2020, are now within a range that is generally viewed as consistent with a healthy labor market.

The number of people continuing to receive benefits after an initial week of aid dropped 134,000 to 2.105 million in the week ended Oct. 23. That was also the lowest level since the middle of March in 2020. The number of people receiving aid has declined by around 75% since early September when government-funded benefits expired.

Falling claims augur well for October’s employment report due on Friday. According to a Reuters survey of economists, nonfarm payrolls likely rose by 450,000 jobs. The economy created 194,000 jobs in September, the fewest in nine months.

U.S. stocks opened higher. The dollar rose against a basket of currencies. U.S. Treasury yields fell.

WORKER SHORTAGE

Expectations for an acceleration in job gains were bolstered by the ADP National Employment Report on Wednesday showing strong growth in private payrolls in October. The Conference Board’s labor market differential – derived from data on consumers’ views on whether jobs are plentiful or hard to get – hit a 21-year high.

But relentless worker shortages remain an obstacle. Caregiving needs during the pandemic, fears of contracting the coronavirus, early retirements and careers changes as well as an aging population have left businesses with 10.4 million unfilled jobs as of the end of August.

Fed Chair Jerome Powell told reporters on Wednesday that “these impediments to labor supply should diminish with further progress on containing the virus, supporting gains in employment and economic activity.”

There are concerns that the White House’s vaccine mandate, which applies to federal government contractors and businesses with 100 or more employees, could add to the worker shortages.

A report on Thursday from global outplacement firm Challenger, Gray & Christmas showed job cuts announced by U.S.-based employers increased 27.5% in October to 22,822, the highest since May. It said 22% of the layoffs were people who refused to be vaccinated as per company requirements.

“The issue could push people out of the labor force or slow re-entry as people extend their searches for either employers not enforcing the mandate or workplaces where it doesn’t apply,” said Ryan Sweet, a senior economist at Moody’s Analytics in West Chester, Pennsylvania.

With workers scarce, companies are raising wages. A second report from the Labor Department on Thursday showed unit labor costs, the price of labor per single unit of output, increased at an 8.3% annualized rate in the third quarter after rising at a 1.1% pace in the April-June quarter.

Labor costs rose at a 4.8% rate compared to a year ago. The report followed on the heels of news last month that wage growth in the third quarter was the largest on record. Strong wage gains, together with rising rents, challenge the Fed’s narrative that high inflation is transitory.

“The rise will add to concerns about inflation becoming more entrenched and/or the growing risk to profits, as businesses are not able to offset higher wage costs via productivity gains,” said Sarah House, a senior economist at Wells Fargo in Charlotte, North Carolina.

Worker productivity fell at a 5.0% rate last quarter, the biggest drop since the second quarter of 1981. That followed a 2.4% growth pace in the April-June period.

A third report from the Commerce Department showed the trade deficit surged 11.2% to a record $80.9 billion in September.

(Reporting By Lucia Mutikani; Editing by Chizu Nomiyama and Andrea Ricci)

U.S. economy slows sharply in third quarter; weekly jobless claims at new 19-month low

By Lucia Mutikani

WASHINGTON (Reuters) – The U.S. economy grew at its slowest pace in more than a year in the third quarter as COVID-19 infections flared up, further straining global supply chains and causing shortages of goods like automobiles that almost stifled consumer spending.

Gross domestic product increased at a 2.0% annualized rate last quarter, the Commerce Department said in its advance GDP estimate on Thursday. That was slowest since the second quarter of 2020, when the economy suffered a historic contraction in the wake of stringent mandatory measures to contain the first wave of coronavirus cases.

The economy grew at a 6.7% rate in the second quarter. The Delta variant of the coronavirus worsened labor shortages at factories, mines and ports, gumming up the supply chain. Economists polled by Reuters had forecast GDP rising at a 2.7% rate last quarter.

Strong inflation, fueled by the economy-wide shortages and pandemic relief money from the government over the course of the public health crisis, cut into growth. Ebbing fiscal stimulus and Hurricane Ida, which devastated U.S. offshore energy production in late August, also weighed on the economy.

Consumer spending, which accounts for more than two-thirds of U.S. economic activity, grew at a 1.6% rate after a robust 12% growth pace in the April-June quarter. Though automobiles accounted for a chunk of the stagnation, the Delta variant also curbed spending on services like air travel and dining out.

But there are signs that economic activity picked up as the turbulent quarter ended. The summer wave of COVID-19 infections has subsided, with cases declining significantly in recent weeks. Vaccinations have also picked up. The improving public health situation helped to lift consumer confidence this month.

Fewer Americans are filing new claims for unemployment benefits. That improving trend in labor market conditions was confirmed by a separate report from the Labor Department on Thursday showing initial claims for state unemployment benefits dropped 10,000 to a seasonally adjusted 281,000 last week, the lowest level since mid-March 2020.

It was the third straight week that claims remained below the 300,000 threshold. Economists polled by Reuters had forecast 290,000 applications in the latest week.

(Reporting by Lucia Mutikani; Editing by Chizu Nomiyama)

Russia reports cases of more contagious COVID-19 Delta subvariant

MOSCOW (Reuters) -Russia has reported “isolated cases” of COVID-19 with a subvariant of the Delta variant that is believed to be even more contagious, the state consumer watchdog’s senior researcher said on Thursday.

The researcher, Kamil Khafizov, said the AY.4.2 subvariant may be around 10% more infectious than the original Delta – which has driven new cases and deaths to a series of record daily highs in Russia – and could ultimately replace it.

However, he said this was likely to be a slow process.

“The vaccines are effective enough against this version of the virus, which is not so different as to dramatically change the ability to bind to antibodies,” he said.

The AY.4.2 subvariant is also on an increasing trajectory in England and had already accounted for about 6% of all sequences generated on the week beginning Sept. 27, a UK Health Security Agency report released on Oct. 15 said.

British Health Minister Sajid Javid on Wednesday said there was no reason to believe the subvariant posed a greater threat than Delta.

Russian immunologist Nikolay Kryuchkov said Delta and its subvariants would remain dominant and might in the future adapt in some ways to vaccines, especially where vaccination rates are below or just above 50%.

“But it seems to me that a revolutionary jump will not happen, because the coronavirus, like any organism, has an evolutionary limit, and the evolutionary jump has already happened,” he said.

The Russian health ministry had no immediate comment.

Moscow’s mayor on Thursday announced the strictest lockdown measures since June of last year, a day after President Vladimir Putin approved a government proposal for a week-long workplace shutdown at the start of November.

(Reporting by Maxim Rodionov, Polina Nikolskaya and Angelina Kazakova; Writing by Olzhas Auyezov; Editing by Mark Trevelyan and Giles Elgood)

Factbox-Latest on the worldwide spread of the coronavirus

(Reuters) – Japan will lift a state of emergency in all regions on Thursday as the number of new cases falls, while India reported the smallest daily rise in COVID-19 deaths since mid-March.

DEATHS AND INFECTIONS

EUROPE

* Sweden will offer additional groups, including people aged 80 and above, to top up their COVID-19 vaccinations with a third dose, the Nordic country’s health minister said.

* Italy’s health ministry said on Tuesday it had given the go-ahead for travel to six non-European tourist spots without the need for quarantine as a COVID-19 precaution either on arrival or return.

AMERICAS

* New York hospitals began firing or suspending healthcare workers for defying a state order to get the COVID-19 vaccine, and resulting staff shortages prompted some hospitals to postpone elective surgeries or curtail services.

* Brazil will provide COVID-19 vaccine booster shots to all its people over 60-years-old, Health Minister Marcelo Queiroga said.

* A Brazilian hospital chain tested unproven drugs on elderly COVID-19 patients without their knowledge as part of an effort to validate President Jair Bolsonaro’s preferred ‘miracle cure,’ a lawyer for whistleblowing doctors told senators on Tuesday.

* Authorities in Costa Rica said on Tuesday all state workers will need to be vaccinated against COVID-19, making it one of the first countries in Latin America to impose a coronavirus vaccination mandate.

ASIA-PACIFIC

* China administered about 3.0 million doses of COVID-19 vaccines on Sept. 27, bringing total doses to 2.203 billion, data from the National Health Commission showed.

* India’s drug regulator has allowed vaccine maker Serum Institute to enroll kids aged 7-11 years for its trial of U.S. drugmaker Novavax’s COVID-19 vaccine.

* Sydney residents who are not vaccinated against COVID-19 risk being barred from various social activities even when they are freed from stay-at-home orders in December.

MIDDLE EAST AND AFRICA

* Egypt is now providing immediate COVID-19 vaccinations at youth centers across the country without prior online registration, a step aimed at encouraging vaccinations and relieving pressure on hospitals and health units amid a fourth wave of infections.

* Algeria will start production of COVID-19 vaccine Sinovac in partnership with China on Wednesday with the aim of meeting domestic demand and exporting the surplus, the prime minister’s office said on Tuesday.

MEDICAL DEVELOPMENTS

* Pfizer and BioNTech have submitted initial trial data for their COVID-19 vaccine in 5-11 year old’s and said they would make a formal request with U.S. regulators for emergency use in the coming weeks.

* Sanofi is dropping plans for its own mRNA-based COVID-19 vaccine because of the dominance achieved by BioNTech-Pfizer and Moderna in using the technology to fight the pandemic, the company said.

* As Merck & Co and Pfizer prepare to report clinical trial results for experimental COVID-19 antiviral pills, rivals are lining up with what they hope will prove to be more potent and convenient oral treatments of their own.

ECONOMIC IMPACT

* Global shares fell for a third successive day on Tuesday, with tech stocks plummeting, as anxiety over when central banks might raise interest rates led to rising bond yields on both sides of the Atlantic.

* Profits at China’s industrial firms grew at a weaker pace in August from a year earlier, slowing for a sixth consecutive month, as manufacturers struggled with high commodity prices, COVID-19 outbreaks and shortages of some key components.

* The East Asia and Pacific region’s recovery has been undermined by the spread of the Delta variant, which is likely slowing economic growth and increasing inequality in the region, the World Bank said.

(Compiled by Ramakrishnan M., Vinay Dwivedi and Juliette Portala; Edited by Arun Koyyur and Shounak Dasgupta)

Biden to outline plan to curb coronavirus Delta variant as cases grow

By Steve Holland and Nandita Bose

WASHINGTON/ABOARD AIR FORCE ONE (Reuters) -President Joe Biden on Thursday will present a six-pronged strategy intended to fight the spread of the highly contagious coronavirus Delta variant and increase U.S. COVID-19 vaccinations, the White House said on Tuesday.

The United States, which leads the world in COVID-19 cases and deaths, is struggling to stem a wave of infections driven by the variant even as officials try to persuade Americans who have resisted vaccination to get the shots. Rising case loads have raised concerns as children head back to school, while also rattling investors and upending company return-to-office plans.

White House spokeswoman Jen Psaki told reporters traveling with Biden aboard Air Force One that he will lay out the six-pronged strategy “working across the public and private sectors to help continue to get the pandemic under control.”

Asked about possible new mandates, Psaki said the White House would offer more details later about the plan and acknowledged that the federal government cannot broadly mandate that Americans get vaccinated.

“We need to continue to take more steps to make sure school districts are prepared and make sure communities across the country are prepared,” Psaki added.

On Wednesday, Biden is scheduled to meet with White House COVID-19 advisers.

The United States has recorded roughly 650,000 COVID-19 deaths and last week exceeded 40 million cases. Reuters data shows that more than 20,800 people have died in the United States from COVID-19 in the past two weeks, up about 67% from the prior two-week period.

Hospitalizations have grown, with seven U.S. states – Alaska, Georgia, Hawaii, Idaho, Kentucky, Tennessee and Washington – reporting records this month.

Biden previously announced plans to offer booster shots more widely, pending regulatory approval. His chief medical adviser Anthony Fauci on Tuesday said officials are still aiming to do so starting the week of Sept. 20.

U.S. Food and Drug Administration advisers are scheduled to meet on Sept. 17 to consider a possible third shot of Pfizer Inc and BioNTech SE’s two-dose vaccine, the only COVID-19 vaccine yet to receive full approval from the agency.

Fauci told CNN Pfizer’s third shot appears likely to be rolled out first, with Moderna Inc’s version “close behind.” Moderna has sought full FDA approval of its two-dose vaccine.

Booster doses are already approved by U.S. regulators for people with compromised immune systems.

U.S. officials have said they expect vaccines to be approved for children younger than 12 this winter. With U.S. students already starting a new school year, battles over public health efforts including mandates that pupils wear masks erupted in many places across the country.

In the private sector, increasing numbers of U.S. employers have imposed vaccine mandates for employees. The Biden administration has hailed efforts by businesses, universities and others to bolster vaccinations.

According to the U.S. Centers for Disease Control and Prevention, 62.3% of Americans have received at least one vaccine dose and 53% – 176 million people – are fully vaccinated. Counting the population eligible for vaccines – people 12 and older – 72.9% have received at least one dose and 62% are fully vaccinated, according to the CDC.

(Reporting by Steve Holland in Washington and Nadita Bose aboard Air Force One; Writing by Susan Heavey; Editing by Will Dunham)

U.S. job growth takes giant step back as Delta variant hits restaurants

By Lucia Mutikani

WASHINGTON (Reuters) – The U.S. economy created the fewest jobs in seven months in August as hiring in the leisure and hospitality sector stalled amid a resurgence in COVID-19 infections, which weighed on demand at restaurants and hotels.

But other details of the Labor Department’s closely watched employment report on Friday were fairly strong, with the unemployment rate falling to a 17-month low of 5.2% and July job growth revised sharply higher. Wages increased a solid 0.6% and fewer people were experiencing long spells of unemployment.

This points to underlying strength in the economy even as growth appears to be slowing significantly in the third quarter because of the soaring infections, driven by the Delta variant of the coronavirus, and relentless shortages of raw materials, which are depressing automobile sales and restocking.

“It is important to keep the right perspective,” said Brian Bethune, professor of practice at Boston College. “Given the supply chain constraints and the ongoing battle to lasso COVID-19 to the ground, the economy is performing exceptionally well.”

The survey of establishments showed nonfarm payrolls increased by 235,000 jobs last month, the smallest gain since January. Data for July was revised up to show a whopping 1.053 million jobs created instead of the previously reported 943,000.

Hiring in June was also stronger than initially estimated, leaving average monthly job growth over the past three months at a strong 750,000. Employment is 5.3 million jobs below its peak in February 2020. Economists polled by Reuters had forecast nonfarm payrolls increasing by 728,000 jobs in August.

Though the Delta variant was the biggest drag, fading fiscal stimulus was probably another factor. The response rate to the survey is lower in August and the pandemic has made it harder to adjust education employment for seasonal fluctuations.

The initial August payrolls print has undershot expectations over the last several years, including in 2020. Payrolls have been subsequently revised higher in 11 of the last 12 years.

“The August payroll figures have historically been revised higher in the years since the Great Recession, sometimes significantly, and there’s a good chance this effect will occur again this time,” said David Berson, chief economist at Nationwide in Ohio.

Employment in the leisure and hospitality sector was unchanged after gains averaging 377,000 per month over the prior three months. Restaurants and bars payrolls fell 42,000 and hiring at hotels and motels decreased 34,600, offsetting a 36,000 gain in arts, entertainment and recreation jobs. Retailers shed 29,000 jobs.

Construction lost 3,000 jobs. There were gains in mining, financial services, information and professional and business services as well as transportation and warehousing.

Manufacturing added 37,000 jobs, led by a 24,100 increase in the automobile industry. Factory hiring remains constrained by input shortages, especially semiconductors, which have depressed motor vehicle production and sales.

General Motors and Ford Motor Co announced production cuts this week.

Motor vehicle sales tumbled 10.7% in August.

That, together with raw materials shortages, which are making it harder for businesses to replenish inventories, prompted economists at Goldman Sachs and JPMorgan to slash third-quarter GDP growth estimates to as low as a 3.5% annualized rate from as high as a 8.25% pace. The economy grew at a 6.6% pace in the second quarter.

Government payrolls fell by 8,000 in August as state government education lost 21,000 jobs. August is the start of the back-to-school season, but the Bureau of Labor Statistics, which compiles the employment report cautioned that “pandemic-related staffing fluctuations in public and private education have distorted the normal seasonal hiring and layoff patterns.”

Stocks on Wall Street were mixed. The dollar slipped against a basket of currencies. U.S. Treasury prices fell.

SILVER LININGS

Details of the smaller household survey from which the unemployment rate is derived were fairly upbeat.

Household employment increased by 509,000 jobs, enough to push the unemployment rate to 5.2%, the lowest since March 2020 from 5.4% in July. The jobless rates, however, continued to be understated by people misclassifying themselves as being “employed but absent from work.” Without this problem, the jobless rate would have been 5.5%.

Even so, a broader measure of unemployment, which includes people who want to work but have given up searching and those working part-time because they cannot find full-time employment, dropped to a 17-month low of 8.8% from 9.2% in July.

Though the participation rate was steady at 61.7%, about 190,000 people entered the labor force last month. Even more encouraging, the number of permanent job losers declined 443,000 to 2.5 million. The number of long-term unemployed dropped to 3.2 million from 3.4 million in the prior month.

They accounted for 37.4% of the 8.4 million officially unemployed people, down from 39.3% in July. The duration of unemployment fell to 14.7 weeks from 15.2 weeks in July.

Economists did not believe the pullback in hiring was enough for the Federal Reserve to back away from its “this year” signal for the announcement of the scaling back of its massive monthly bond buying program, given strong wage growth.

“For the Fed a taper announcement is still likely coming in either November or December,” said Michael Feroli, chief U.S. economist at JPMorgan in New York.

The 0.6% jump in average hourly earnings after a 0.4% rise in July boosted annual wage growth to 4.3% in August from 4.0% in the prior month. The increase, led by lower-paying industries, is the result of worker shortages caused by the pandemic. There were a record 10.1 million job openings at the end of June.

There is cautious optimism that the labor pool will increase because of schools reopening and government-funded benefits expiring on Monday. But the Delta variant could delay the return to the labor force by some of the unemployed in the near term.

About 41,000 women, 20 years and older, dropped out the labor force. The number of number of people saying they were unable to work because of the pandemic increased 497,000 in August, the first rise since December. There was also a slight rise in the number of people working from home.

(Reporting by Lucia Mutikani; Editing by Chizu Nomiyama and Andrea Ricci)

Pennsylvania governor issues mask mandate for schools, child care facilities

By Brendan O’Brien

(Reuters) -Pennsylvania Governor Tom Wolf on Tuesday issued a mask mandate for all K-12 school and child care facilities to protect against the spread of COVID-19, three weeks after the Democrat said he would leave the decision to individual districts.

The order, which goes into effect Sept. 7, comes amid a surge in COVID-19 cases due to the highly-contagious Delta variant of the virus.

Since July, Pennsylvania’s COVID-19 case load has increased from less than 300 a day to more than 3,000 a day, according to the state’s health department.

“With case counts increasing, the situation has reached the point that we need to take this action to protect our children, teachers and staff. The science is clear,” the state’s acting Health Secretary Alison Beam said in a statement.

The decision comes as millions of public education students head back to schools across the United States. School districts, state education agencies and governors across the nation are grappling with masking and vaccination requirements.

In South Carolina, for example, the state’s supreme court heard arguments on Tuesday in two cases involving mask mandates in city of Columbia schools.

The order in Pennsylvania requires students, teachers and staff to wear masks in all public and private K-12 schools. The order also applies to child care providers and early learning programs. The order does not apply to school sports or outdoor activities.

In early August, Wolf said he intended to leave the decision to require masks in schools up to individual districts.

“Unfortunately, an aggressive nationwide campaign is spreading misinformation about mask-wearing and pressuring and intimidating school districts to reject mask policies that will keep kids safe and in school,” he said.

(Reporting by Brendan O’Brien in Chicago; Editing by Chris Reese and Bill Berkrot)

More contagious Delta variant makes people sicker; oral drug shows promise in treating COVID-19 pneumonia

By Nancy Lapid

(Reuters) – The following is a summary of some recent studies on COVID-19. They include research that warrants further study to corroborate the findings and that have yet to be certified by peer review.

Delta variant makes people sicker

The Delta variant of the coronavirus is known to be more easily transmissible than earlier versions, and now a large UK study suggests it also makes people sicker. Researchers analyzed data on 43,338 patients infected with either the Alpha or the Delta variant. Overall, roughly three quarters were unvaccinated, and half were under age 31. After accounting for patients’ underlying risk factors, researchers found that unvaccinated patients were 132% more likely to be hospitalized if they were infected with Delta than with Alpha. Vaccinated patients may also be more likely to require hospitalization with a Delta infection, but data for those patients was less clear, according to a report published on Friday in The Lancet Infectious Diseases. The results “suggest that outbreaks of the Delta variant in unvaccinated populations might lead to a greater burden on healthcare services than the Alpha variant,” the researchers concluded.

Oral drug shows promise against COVID-19 pneumonia

Severely ill patients with COVID-19 pneumonia who received the experimental oral drug opaganib developed by RedHill Biopharma required less extra oxygen and were able to leave the hospital sooner than patients receiving a placebo in a small randomized trial, researchers reported on Sunday on medRxiv ahead of peer review. Within 14 days after enrolling in the study, 50.0% of patients taking opaganib no longer needed oxygen, compared to 22.2% of patients in the placebo group. In addition, 86.4% of opaganib-treated patients had been discharged, versus 55.6% in the placebo group. On Thursday, RedHill announced that opaganib strongly inhibits the Delta variant of the coronavirus in test tube experiments. The drug is believed to exert its antiviral effect by inhibiting sphingosine kinase-2 (SK2), a key enzyme in cells that may be recruited by the virus to support its replication, the company said. Based on the initial 42-patient trial conducted last year, RedHill Biopharma launched a much larger randomized trial in patients hospitalized with severe COVID-19 pneumonia. The last of the 475 patients in that late-stage study has now completed treatment and some of the data should be available soon, the company said last week.

Seizure in children may signal COVID-19

Seizures may be the only symptom of COVID-19 in some children, a new report cautions. Children tend to get sick from COVID-19 far less often than adults, and their symptoms are usually not severe, mainly consisting of fever and mild respiratory issues, although more have become ill with emergence of the Delta variant. Among 175 children who came to an Israeli emergency room and were diagnosed with COVID-19, 11 were brought to the hospital because of seizures, researchers reported on Saturday in the medical journal Seizure. Only seven had previously been diagnosed with a neurological disorder, and only six had fever. All 11 made full recoveries. While seizures have not been a frequently reported problem in adults with COVID-19, they “may be the main manifestation of acute COVID-19 in children,” even without fever and without a history of epilepsy, the study authors said. In some hospitals, they point out, only children with flu-like symptoms or close contact with a confirmed COVID-19 patient get tested for the coronavirus. Medical personnel should be aware that children with seizures should be tested, too, they said.

(Reporting by Nancy Lapid; Editing by Bill Berkrot)